The abuse of synthetic cannabinoids by teenagers, young adults, and the homeless population has led to thousands of hospitalizations and overdose deaths over the past several years. These compounds are sold by international manufacturers and imported legally into the U.S. due to the synthesis of banned substance variants outpacing the DEA’s ability to identify them. We recently learned that the synthetic cannabinoid problem extends into to the business of legal cannabis production. A number of growers in the Pacific Northwest have been caught spraying their harvests with these synthetic compounds to increase the perceived potency of their products. Consumer safety is at risk while states like Washington, Oregon, and others work towards consensus on testing requirements and standardization of methods.